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Industrial Stage 2 MULTI-CHANNELS FLOW-RATE CONTROL BASED ON PRESSURE ACTUATION Presenter: Anne Le Nel, R&D Manager Time: Monday 28 October, 14:15 - 14:30 Fluigent SA Biopark 1 mail du Professeur Georges Mathé Villejuif, 94800 FRANCE phone: +33-17-701-8268 email: contact@fluigent.com www.fluigent.com We present a new algorithm which enables the flow-rate control of a microfluidic system using pressure actuators. The algorithm combines the benefits of pressure flow actuation in terms of stability and responsiveness with the direct flow-rate control of the system. The algorithm can address a full range of multi-channel configurations including strong channel coupling. The matrix approach is by far much more powerful than a PID loop and involves an identification step during which all the interdependencies between applied pressures and measured flow-rates are identified and the hydrodynamic modeling computed. The algorithm can be applied to complex systems with cross-talks between channels or a massively parallel system with independent channels, regardless of the number of channels. We tested the performances of this new flow-rate control solution and compared them to the performances of a high precision syringe pump-based solution. The results show higher stability, higher responsiveness and lower cross-talks between channels. Several applications using this new flow control solution will also be presented. |