Program » Plenary Speakers

DIAGNOSTICS FROM BENCH TO BEDSIDE: INNOVATION TO DRIVE IMPACT
Rosanna Peeling
London School of Hygiene and Tropical Medicine, UK

In 2015, countries committed to a set of 17 Sustainable Development Goals (SDGs), calling for Universal Health Coverage with no one left behind. Efforts to achieve the SDGs need to be underpinned by affordable diagnostic tests that can be used at the point of care. Innovation in diagnostics is urgently needed not only to provide clinical decision support but also to address epidemic preparedness and antimicrobial-resistance. To drive impact, technological innovation needs to be accompanied by delivery mechanisms that ensure equitable access to quality-assured diagnostics.

ENGINEERING CELLS AND MICROSYSTEMS TO STUDY MECHANOBIOLOGY
Beth Pruitt
University of California, Santa Barbara, USA

Understanding the mechanical basis of homeostasis (health) and defective cell renewal function (disease) increasingly requires us to consider the role of mechanics. To study how cells and tissues integrate mechanical signals, we deploy specialized cell culture systems and micromachined tools to stimulate and measure forces and displacements at the scale of proteins and cells. We are particularly interested in leveraging induced pluripotent stem cells to create human models of cardiac development and disease.

ORGANOIDS MEET ORGAN CHIPS
Jianhua Qin
Chinese Academy of Sciences (CAS), CHINA

Organoids and organ chips are novel in vitro miniaturized model systems of human organs that have gained enormous interest for recapitulating tissue physiology, diseases and for drug screening. However, achieving high-fidelity 3D tissues for real-life application is still a major outstanding challenge. In this talk, I will present our efforts to integrate two distinct strategies toward a synergistic engineering of living systems that might offer promising platform for organ development, disease etiology, drug testing and virology research.

WOMEN INSPIRED STRATEGIES FOR HEALTH: TACKLING CANCER PREVENTION AND CONTROL FROM DIFFERENT ANGLES
Nimmi Ramanujam
Duke University, USA

In my talk, I will discuss how disruptive approaches to both technology innovation and health care delivery models could broaden access to preventive services and effective care. Point of care technologies that can work in the hands of non-experts will be key to making this shift. This idea of decentralized care is not entirely new. Historically, before advanced medical technologies were invented much of medical care was provided at the community level or in the patient's home. While hospitals have transformed health in countries like the United States, this model is no longer sustainable, particularly in low resource settings. My talk will focus on technologies we are developing to support more patient-centered approaches to healthcare delivery and how we are moving forward to leverage these tools towards sustainable impact at scale for cervical cancer prevention.

INTEGRATING ACOUSTOPHORESIS TO DROPLET MICROFLUIDICS
Maria Tenje
Uppsala University, SWEDEN

Droplet microfluidics provides a platform for miniaturisation of biological and chemical experiments on-chip. To transfer biological assays onto the droplet microfluidic platform, several unit operations are needed. My research lab has shown the integration of acoustic manipulation to droplet microfluidics to expand the droplet unit operation toolbox, especially focused on controlled liquid exchange and particle enrichment. In this presentation, I will describe how the technology works, discuss the challenges involved and share our latest results.

SELF-POWERED INTEGRATED SMART SYSTEM
Haixia (Alice) Zhang
Peking University, CHINA

With the blooming of consumer electronics and sensor network in the past decades, the vast applications and wide distributions of low-power consumption mobile electronics have reached every corner of our daily life, also make another story about energy beyond conventional batteries with limit life, which we named it as self-powered Integrated Smart System. In this talk, we start with high performance TENG based hybrid nanogenerator, then multi-functional active sensors and actuators based on the same principle, including the method to mimic human skin with stretch ability and conductivity. Furthermore, biocompatibility, self-healing and humidity-resistance are also stated. Finally, some demonstrations of self-powered smart system, for example, skin-on-chip, smart watch, health monitor patch, will be introduced. The perspective of this field will be discussed in the last.